Brooks Koepka announced Wednesday that he has withdrawn from the Presidents Cup due to a knee injury.

Tiger Woods selected Rickie Fowler to replace Koepka on his 12-man United States team that will play an International squad at The Royal Melbourne Golf Club in Australia from Dec. 9-15.

"Today, I am announcing my withdrawal from the USA Presidents Cup team because of my knee injury," Koepka said in a statement.

"I notified Captain Tiger Woods that despite constant medical care and rehab, I am not able to play golf at this time. I consider it to be a high honor to be part of the 2019 team and I regret not being able to compete.

"Since my injury in Korea, I have been in constant contact with Tiger and assured him that I was making every effort to be 100 percent in time for the Presidents Cup in Australia. However, I need more time to heal.

"I'm sorry I won't be able to represent the Red, White, and Blue this time around and I wish my teammates nothing but the best as they work to retain the Presidents Cup for the USA."

Koepka has not competed since he withdrew from the CJ Cup in South Korea last month.

"Brooks and I talked, and he's disappointed that he won't be able to compete," Woods said. "I told him to get well soon, and that we're sorry he won't be with us in Australia. He would clearly be an asset both on the course and in the team room."

Though he finished in the top five in all four major golf events this year, Koepka revealed in early October that he recently received a stem-cell injection to help repair a partially torn left patellar tendon.

Koepka underwent the painful procedure shortly after the Tour Championship in late August, where he tied for third place.

Fowler will make his third appearance on the U.S. Team.

"I spoke to Rickie and he has agreed to join the U.S. Team," Woods said. "Rickie has played on a couple Presidents Cup teams, was someone seriously considered for a pick and is well respected and liked by his teammates. I know he's going to do a great job for us. We're all excited about this year's event. The course is outstanding, the fans will be loud and we're playing against great competitors. We're ready to go."